Generation of Reactive Oxygen Species by Mitochondria
نویسندگان
چکیده
منابع مشابه
Cardiac mitochondria and reactive oxygen species generation.
Mitochondrial reactive oxygen species (ROS) have emerged as an important mechanism of disease and redox signaling in the cardiovascular system. Under basal or pathological conditions, electron leakage for ROS production is primarily mediated by the electron transport chain and the proton motive force consisting of a membrane potential (ΔΨ) and a proton gradient (ΔpH). Several factors controllin...
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The mitochondrial respiratory chain is a major source of reactive oxygen species (ROS) under pathological conditions including myocardial ischemia and reperfusion. Limitation of electron transport by the inhibitor rotenone immediately before ischemia decreases the production of ROS in cardiac myocytes and reduces damage to mitochondria. We asked if ROS generation by intact mitochondria during t...
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Copyright © 2009 American Heart Association. All rights reserved. Print ISSN: 0194-911X. Online 72514 Hypertension is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX DOI: 10.1161/HYPERTENSIONAHA.109.130054 2009;53;885-892; originally published online Apr 27, 2009; Hypertension Francesco Addabbo, Monica Montagnani and Michael S. Goligorsky Mitochondria and Reactiv...
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ژورنال
عنوان ژورنال: Antioxidants
سال: 2021
ISSN: 2076-3921
DOI: 10.3390/antiox10030415